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Fructose is a simple monosaccharide found in many plant foods and is widely used as a sweetening additive in the form of fructose corn syrup, a mixture of glucose and fructose. Its consumption has risen in recent years.
Non-absorbed fructose produces gastrointestinal symptoms in the large bowel when metabolised by colonic bacteria, which may be a cause of recurrent abdominal pain. It has also been suggested that fructose malabsorption may underlie the gastrointestinal symptoms seen in patients with irritable bowel syndrome (IBS) [2]. Genetic mutations can increase an individual’s susceptibility.
Breath testing is the method of choice for the diagnosis of fructose intolerance. 25 g of fructose is the cut-off dose to investigate fructose malabsorption, with a positive breath test at this dose suggesting poor fructose absorption capacity. This low level may be regularly consumed in the daily diet, resulting in frequent symptoms of fructose malabsorption [4].
Fructose malabsorption should be considered in subjects with unexplained gastro-intestinal symptoms, especially after consumption of fruit and fruit drinks. Fructose malabsorption may also contribute to the symptoms of IBS.
Test datasheet: Fructose Intolerance datasheet
Sample report: Fructose Intolerance Breath Test sample report
Patient instruction sheet: Fructose Intolerance Breath Test patient instructions.
Receive a personalised, written report from our Functional Medicine practitioner, Despina Giannopoulou, based on your test results.
After purchase, please complete the form linked in your confirmation email.
She will review the results and provide interpretation along with a recommended treatment plan. Follow-up calls to discuss your results and treatment in more depth can be arranged directly with Despina.
Despina Giannopoulou is a Certified Functional Medicine Practitioner as well as holding a Masters in Personalised Nutrition from CNELM, a clinical naturopathic nutrition diploma from CNM, a Bulletproof Human Potential Coaching Certification, a Bachelors in Computer Science and an MBA.
Indications:
Research overwhelmingly indicates that gut health impacts overall health. The gut microbiome, in particular, plays a critical role in mediating the effects of diet and other factors on health, including digestive, immune, metabolic and neuroendocrine functions. Assessing GI health with the proper tools can help practitioners get to the root cause of chronic illness.
The GI-MAP (Microbial Assay Plus) is unique in the field of comprehensive stool testing. It relies on quantitative polymerase chain reaction (qPCR) technology to detect parasites, bacteria (including Helicobacter Pylori), fungi & viruses by targeting the specific DNA of the organisms tested.
Additionally, the screen includes the chemistry markers, Steatocrit, Pancreatic Elastase, β-Glucuronidase, Occult blood (faecal immunochemical test – FIT), Secretory IgA, Anti-gliadin IgA, Eosinophil Activation Protein and Calprotectin.
Sample Collection Instructions: GI-Map collection instructions
Sample Report: GI-MAP – sample report
Interpretive Guide: GI-Map Interpretive Guide
Postal Samples: Accepted
Lactose, a disaccharide, is not normally absorbed directly from the gut, but is broken down into glucose and galactose by the enzyme lactase. If the lactase is absent (or insufficient for the dietary load of lactose), then non-absorbed lactose will be the pass into the lower small intestine and the colon. This may result in diarrhoea with cramps and flatulence, the symptoms of the condition known as “lactose intolerance”, which is not an allergic condition but a digestive problem.
In such cases, the lactose, on reaching the large bowel is fermented by colonic bacteria producing hydrogen and sometimes methane. These gasses pass across the gut wall into circulation and are exhaled in the breath.
This test requires the collection of breath samples after avoiding dietary fibre, resistant starch, complex carbohydrates and dairy products for 24 hours, followed by an overnight fast. An initial breath sample is collected, the patient then consumes 25G of lactose (supplied with the test kit) and then further breath samples hourly for three hours. A negative test will return very low levels of hydrogen and methane throughout, whereas a patient with lactose intolerance will exhibit raised levels of breath gasses when the lactose reaches the colon, as illustrated in the sample report which can be viewed below.
Test datasheet: Lactose Intolerance datasheet
Sample report: Lactose Intolerance Breath Test sample report
Patient instruction sheet: Lactose Intolerance Breath Test patient instructions.
Irritable Bowel Syndrome (IBS) symptoms lasting for days, weeks or months occurs in up to 13 million UK residents, the majority female. Post-exclusion of other pathologies, a diagnosis of Small Intestinal Bacterial Overgrowth is frequently made which can be treated with antibiotics or natural antimicrobials.
The analysis of alveolar breath hydrogen and methane, fermentation products of intestinal bacteria post-ingestion of carbohydrates, is a well-proven method for screening patients for SIBO (and carbohydrate intolerances), enabling both rapid diagnosis and treatment monitoring. Our easy-to-use home-sampling test kits enhance the availability of this diagnostic methodology.
We have undertaken the most comprehensive analytical and validation process for SIBO testing. Our methodology utilises 10 samples (at 20-minute intervals) which allows for a higher degree of reporting accuracy compared to protocols using fewer samples. This, combined with our experience in the interpretation of tests in this class, enables us to fully support practitioners in the interpretation of these test results.
Sample report: SIBO sample report
Test datasheet: Small Intestinal Bacterial Overgrowth
Test kit instructions: SIBO Patient Instructions
Receive a personalised, written report from our Functional Medicine practitioner, Despina Giannopoulou, based on your test results.
After purchase, please complete the form linked in your confirmation email.
She will review the results and provide interpretation along with a recommended treatment plan. Follow-up calls to discuss your results and treatment in more depth can be arranged directly with Despina.
Despina Giannopoulou is a Certified Functional Medicine Practitioner as well as holding a Masters in Personalised Nutrition from CNELM, a clinical naturopathic nutrition diploma from CNM, a Bulletproof Human Potential Coaching Certification, a Bachelors in Computer Science and an MBA.
Indications:
Research overwhelmingly indicates that gut health impacts overall health. The gut microbiome, in particular, plays a critical role in mediating the effects of diet and other factors on health, including digestive, immune, metabolic and neuroendocrine functions. Assessing GI health with the proper tools can help practitioners get to the root cause of chronic illness.
The GI-MAP (Microbial Assay Plus) is unique in the field of comprehensive stool testing. It relies on quantitative polymerase chain reaction (qPCR) technology to detect parasites, bacteria (including Helicobacter Pylori), fungi & viruses by targeting the specific DNA of the organisms tested.
Additionally, the screen includes the chemistry markers, Steatocrit, Pancreatic Elastase, β-Glucuronidase, Occult blood (faecal immunochemical test – FIT), Secretory IgA, Anti-gliadin IgA, Eosinophil Activation Protein, Calprotectin & Zonulin
Sample Collection Instructions: GI-Map collection instructions
Sample Report: GI-MAP – sample report
Interpretive Guide: GI-Map Interpretive Guide
Postal Samples: Accepted
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